Pharmaceutical K4M

Basic Information

• Chemical Name: Hydroxypropyl Methylcellulose.

• Specification: The "K4000" in its name represents its viscosity specification. In a 2% aqueous solution at 20℃, its viscosity is approximately 4000mPa·s.

Physicochemical Properties

• It appears as a white or off - white powder, odorless and tasteless. It can dissolve in water to form a clear or slightly turbid colloidal solution, and has good water - solubility and thermal stability.

Medicinal Functions

• As a Binder: It can increase the adhesive force between drug powders, making it easier for drug particles to form into tablets, improving the hardness and smoothness of tablets, and contributing to the improvement of the formability and stability of drugs.

• As a Coating Material: It can form a protective film on the surface of drugs, playing roles such as moisture - proofing, light - shielding, and air - isolating. It can also regulate the drug release rate to achieve slow - release or controlled - release effects.

• As a Suspending Agent: It can increase the viscosity of suspensions, evenly disperse drug particles in the liquid medium, prevent particle sedimentation, and improve the stability of suspensions.

• As a Thickener: It is used to adjust the viscosity of liquid pharmaceutical preparations, improve their rheological properties, and make the preparations have suitable fluidity and stability, which is convenient for production and use.

Safety

• Pharmaceutical - grade HPMC K4000 has a high safety profile. It is generally considered non - toxic and non - irritating. It is not digested and absorbed in the body and is excreted in the feces in its original form, having basically no adverse effects on the human body.

Application Range

• It is widely used in the fields of oral solid preparations, liquid preparations, and external preparations, such as tablets, capsules, suspensions, eye drops, ointments, etc.

Shijiazhuang Zhongshuo Pharmaceutical Co., Ltd